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MD Anderson Cancer Center Executive Director, ORBIT Platform in Houston, Texas

The mission of The University of Texas MD Anderson Cancer Center is to eliminate cancer in Texas, the nation and the world through outstanding programs that integrate patient care, research and prevention, and through education for undergraduate and graduate students, trainees, professionals, employees and the public.

The Executive Director for Biologics & Immunotherapy Translation Platform (ORBIT) is responsible for leading all aspects of the scientific activities dedicated to the discovery and development of innovative therapeutic antibody discovery and development including IND-enabling preclinical studies. Consistent with the institution's mission, vision, core values and strategic plan, this position will collaborate with various Clinical Departments, Legal, Business Development, Strategic Industry Ventures, Innovation, Development, Human Resources, and others to develop strategic design, operations, programs, projects and functions and to ensure efficient and effective operations.

KEY FUNCTIONS

  1. Develop framework and lead execution for MD Anderson's innovative anti-cancer monoclonal antibodies for cancer therapy.

  2. As a member of the leadership team, design, develop and implement comprehensive preclinical monoclonal antibody development plans, including biomarker strategy, to guide early clinical development.

  3. Build, and lead a team of scientists conducting discovery and translational research to advance (1) Antibody discovery & engineering; (2) Program biology; (3) Target biology and (4) In vivo pharmacology into early clinical development.

  4. Function as a key member of TDD senior leadership team, setting strategy and course, and ensuring cross-functional coordination.

  5. Apply expertise in the field of biologics discovery to influence and adapt ORBIT strategy through ongoing evaluation of the field and pivot the overall strategy and program progression as required.

  6. Identify, build and manage additional collaborative relationships with external groups to bring additional projects into the portfolio.

  7. Provide functional and technical management to scientific personnel within the group.

  8. Write and review manuscripts for publication.

  9. Lead data interpretation/analysis, discussion and presentation on behalf of project teams to both internal and external stakeholders, and generate reports, including those for regulatory filings.

  10. Collaborate with clinical developments teams to design and execute preclinical studies to address specific requirements for candidate selection and clinical studies.

  11. Collaborate with clinical teams to lead the preparation and development of IND applications to enable clinical trials.

  12. Recruit and maintain a top-notch collaborative and innovative team.

EDUCATION

Required: PhD, MD or equivalent degree in Biology, Cell Biology, Pharmacology or related field.

EXPERIENCE

Required: At least ten (10) years of industry or industry-like experience in biological drug discovery research. Experience must include supervisory and leadership experience. Must have strong background in biology, antibody engineering and drug discovery.

Preferred: Experience in biological drug discovery processes and requirement for successful clinical development. First-hand experience and successful record of accomplishment in antibody drug discover characterization and lead optimization.

Institute Head, ORBIT Platform It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html

Additional Information

  • Requisition ID: 149956

  • Employment Status: Full-Time

  • Employee Status: Regular

  • FLSA: exempt and not eligible for overtime pay

  • Work Week: Days

  • Fund Type: Hard

  • Work Location: Onsite

  • Minimum Salary: US Dollar (USD) 0

  • Midpoint Salary: US Dollar (USD) 0

  • Maximum Salary : US Dollar (USD) 0

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