MD Anderson Cancer Center Institute Research Scientist - In-Vitro Pharmacology in Houston, Texas
The Institute Research Scientist - In-Vitro Pharmacology participates in cross-functional research to discover novel oncology therapeutic agents to benefit patients.
MD Anderson is known for providing cancer patients with exceptional care, which includes early access to innovative new treatments through clinical trials. The Institute for Applied Cancer Science (IACS) is a new hybrid model that uniquely combines the drug discovery capabilities of the biopharmaceutical industry and the extensive knowledge of biology found in academia with the expertise of MD Anderson's top clinicians. IACS has the singular goal of rapidly developing novel, effective and safe therapeutics that improve patient health. IACS executes programs with the highest probability of clinical success in a rigorous, goal-oriented, data-driven manner. We are seeking a highly motivated and team-oriented individual to join our in vitro Pharmacology group to support our fast-paced drug discovery programs.
Salary range: Min $98,000 - Mid $122,500 - Max $147,000
1.Apply expertise in biochemistry (including enzymology), biophysics, and cell biology to enable drug discovery with novel targets; provide in vitro pharmacology leadership on multidisciplinary drug discovery teams.
2.Responsible for the design and execution of robust biochemical, biophysical, and cellular assays to support target validation, hit identification and confirmation, and lead optimization in small molecule drug discovery projects.
3.Fully characterize mechanism of action and kinetics of lead molecules using biochemical and biophysical techniques.
4.Contribute to project teams through lab-based activities.
5.Work closely with research teams to identify and recommend opportunities leading to scientific discovery and clinical therapeutic drug development.
6.Interact across cross-functional groups, including biology and medicinal chemistry, on discovery-based project teams.
7.Transfer assays to collaborators as appropriate.
8.Employ safe lab practices
9.Maintain research records and laboratory notes.
Required: Bachelor's degree in Biology, Biochemistry, molecular biology, cell biology, enzymology, pharmacology, chemistry or related field.
Preferred: PhD in enzymology, pharmacology, chemistry or related field.
Required: Ten years of relevant research laboratory experience. With Master's degree, eight years of required experience and with PhD, two years of required experience.
Preferred: At least two years of relevant industrial experience within the pharmaceutical industry. Cellular assay experience in a drug discovery setting required.
Ideal Candidate will possess the following:
•Strong enzymology background
•Experience with a wide variety of protein targets in a drug discovery setting
•A demonstrated track record in the development and implementation of in vitro assays for compound screening using a variety of detection formats
•Experience with both 2D and 3D cellular assay systems in a drug discovery setting
•Experience operating automated liquid handling instrumentation
•Strong data analysis skills, ability to interpret results and contribute to the design of follow-up experiments
•Excellent written and oral communication skills.
•High attention to detail
•Ability to work well under pressure and meet critical timelines
•Collaborative attitude and the ability to work effectively on multi-disciplinary project teams
•A desire to train and supervise associate scientists
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html