MD Anderson Cancer Center Research Investigator - Immunology - ECLIPSE in Houston, Texas
The mission of The University of Texas M. D. Anderson Cancer Center is to eliminate cancer in Texas, the nation, and the world through outstanding programs that integrate patient care, research and prevention, and through education for undergraduate and graduate students, trainees, professionals, employees and the public.
ECLIPSE (Co-evolution of Leukemia and Immunity Post Stem Cell Transplant) is a novel organization within the Therapeutics Discovery and Department Division of The University of Texas MD Anderson Cancer Center in Houston, Texas, with the mission of making MDACC and its partners recognized leaders in the identification and development of innovative immunooncology therapies that will cure all hematologic malignancies. https://www.mdanderson.org/cancermoonshots/research_platforms/eclipse.html
We are seeking an experienced and highly motivated individual with deep understanding and hands-on knowledge of automation and various high throughput approaches to drive projects focused on the identification and validation of therapeutic targets for patients with advanced hematologic malignancies. The Institute Research Investigator will participate in cross-functional research developing and implementing state-of-the-art techniques to identify and validate novel immunotherapy targets for hematological malignancies. Specifically, the position calls for development of workflows for, and maintenance of the Beacon Berkeley Lights instrument in ECLIPSE, an optofluidic platform with high throughput capacity for identification of specific immune cells. The selected candidate will be expected to work primarily at the bench, and must be able to independently design, execute, interpret, and troubleshoot experiments. Furthermore, the selected candidate will propose next steps and provide critical feedback on scientific plans.
• Optimize/implement workflow strategies for cutting-edge, high-throughput instruments such as the Beacon.
• Collaborate with cancer biology and computational biology team members on a discovery platform; apply scientific expertise in immunology and/or cancer biology to drive these programs in a multidisciplinary and exciting research team environment.
• Independently design, execute, interpret, and troubleshoot experiments to answer key scientific questions. Use data to make decisions and new hypotheses.
• Keep abreast of current and emerging technological and scientific advancements in the field.
Required: Bachelor's degree in biology, biochemistry, molecular biology, cell biology, enzymology, pharmacology, chemistry or related field.
Preferred: PhD in Immunology/cancer biology or a related discipline
Required: Six years experience of relevant research experience in laboratory With Master's degree, four years of required experience. With a PhD in a natural science or Medical degree, no experience required.
• Experience in T cell biology.
• Hands-on experience with primary T cell culture, flow cytometry, T cell functional assays.
• Ability to independently design, execute, interpret, and troubleshoot experiments. Ability to use results to propose and design follow-up experiments.
• Attention to detail, excellent record keeping abilities.
• Track-record of productivity, demonstrated by publication in respected, peer reviewed journals, and/or patent filings.
• Ability to clearly communicate results to co-workers, collaborators, and leadership.
• Experience in molecular biology techniques such as PCR and qPCR assays.
• Experience in setting up workflows and troubleshooting with liquid handling systems.
• Experience in multi-parametric flow cytometry.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
Requisition ID: 137454
Employment Status: Full-Time
Employee Status: Regular
FLSA: exempt and not eligible for overtime pay
Work Week: Days
Fund Type: Soft
Pivotal Position: Yes
Minimum Salary: US Dollar (USD) 85,000
Midpoint Salary: US Dollar (USD) 106,250
Maximum Salary : US Dollar (USD) 127,500
Science Jobs: No