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MD Anderson Cancer Center Postdoc Fellow - Dr. Ajani's Lab in MDA-On-Site, United States

Dr. Ajani Lab within the Department of GI Medical Oncology at UT MD Anderson Cancer Center is seeking talented and innovative Postdoctoral Fellows to join our team and contribute to groundbreaking research in the field of gastric cancer. As a member of our team, you will have the opportunity to work with multi-omics and gastric cancer GEMM exploring the fundamental and translational biological questions in peritoneal metastasis of gastric cancer. We are particularly interested in applicants who are passionate about developing therapeutic strategies that enhance the quality of life for patients with peritoneal metastasis of gastric cancer. You will play a critical role in selecting potential targets of peritoneal metastasis by scRNA-seq in gastric cancer and regulatory mechanisms of tumorigenesis. We also aim to explore the molecular mechanisms underlying inter- and intra-tumoral heterogeneity and tumor-immune interactions. We seek to explore the novel target and its molecular features contribute to peritoneal metastasis of gastric cancer and shape therapeutic responses.

LEARNING OBJECTIVES

At Dr. Ajani's Lab, our main goal is to provide our Postdoctoral Fellows with an intellectually stimulating, collaborative, and supportive research environment. Our multi-omics platform and gastric cancer GEMM model allow for the investigation of tumor microenvironment, immune response, molecular mechanisms, oncogenic signaling pathways, tumor heterogeneity, and drug responses. We aim to train our fellows in multi-omics and high-throughput genetic screening approaches to further advance peritoneal metastasis of gastric cancer.

As part of their training, our Postdoctoral Fellows will work closely with the PI to gain experience in grant and manuscript writing, as well as manuscript review for journals. They will equip them with the skills required for successful grant applications and the publication of their research.

Additionally, our Postdoctoral Fellows will be expected to present their work at group meetings. We also encourage them to present their research at international conferences to expand their network and find potential collaborations and future employment opportunities.

Finally, we encourage our Postdoctoral Fellows to engage in numerous collaborative projects, as scientific research is typically carried out in teams of investigators with complementary expertise and strengths. As such, they will participate in several ongoing collaborations, and we highly encourage them to initiate and formulate new projects and collaborations.

ELIGIBILITY REQUIREMENTS

With Ph.D., no experience required. With M.D., two years of experience in experimental or scientific work. We expected the Postdoctoral Fellows will be collaborated with team members and apply scientific expertise in molecular biology, immunology and/or cancer biology to drive projects in a multidisciplinary and exciting research team environment. Candidates has in-depth knowledge and skills to elucidate disease mechanisms and cell signaling pathways in GI malignancies.

Experience with performing scRNA-seq and spatial transcriptomics is highly desired. Performs molecular biology experiments such as subcloning, genetic knockout or overexpression of target genes, ELISA, Western blotting, q-PCR, IP, CHiP assay, protein-protein or RNA-Protein interactions, Flow cytometry and drug screening; mouse handling such as tumor injection from clinical specimen, drug treatment and analyze all data as well as genetic mouse model handling. 3 years' experience of postdoctoral fellow is encouraged.

We encourage our Postdoctoral Fellows to assist in preparation of drafts of research grants, manuscripts and grant reports. Ensures that relevant data is collected at designed stages in the research process, is entered into database(s) and reported, as required.

POSITION INFORMATION

MD Anderson follows the NIH stipend levels as outlined by the Kirchstein - NRSA (https://grants.nih.gov/grants/guide/notice-files/NOT-OD-23-076.html) . This full-time trainee position will provide a salary between $56,484 to $68,604, dependent upon the years of postgraduate experience.

MD Anderson offers compensated trainees:

  • Paid medical benefits (zero premium) starting on first day for trainees who work 30 or more hours per week

  • Group Dental, Vision, Life, AD&D and Disability coverage

  • Paid Education Vacation and Sick Leave

  • Paid institutional holidays, wellness leave, childcare leave and other paid leave programs

  • Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans

  • Employer paid life, AD&D and an illness-related reduced salary pay program

  • Health Savings Account and Dependent Care Reimbursement flexible spending accounts

  • Fertility benefits

  • State of Texas longevity pay

  • Extensive wellness, fitness, employee health programs and employee resource groups

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