Job Information
MD Anderson Cancer Center Postdoctoral Fellow - Genitourinary Medical Oncology - Research in MDA-On-Site, United States
The main research goal of the Genitourinary Medical Oncology department is to identify important biological markers to help determine which patients are at the greatest risk of advanced GU disease and metastasis. In alignment with this departmental goal, this postdoctoral project will focus on delineating cellular and molecular mechanisms dictating resistance to chemotherapy, targeted therapy, and immunotherapy in aggressive variant metastatic prostate cancers (a subset with poor prognosis) and link them to clinicopathological features of the disease. Knowledge gained will be used to identify molecular biomarkers and rational therapeutic combinations for treating these aggressive prostate cancers.
To study cellular and molecular mechanisms dictating resistance to chemotherapy, targeted therapy, and immunotherapy in aggressive variant prostate cancers and link them to clinicopathological features of the disease. Knowledge gained will be used to identify biomarkers and rational therapeutic combinations for treating these cancers.
LEARNING OBJECTIVES
Learn the basics of clinical and pathological therapy response and resistance in aggressive variant prostate cancers.
Become proficient in the intersection of tumor immune microenvironment, tumor metabolism, tumor genomics and epigenomics, disease progression, and treatment response in patients with aggressive variant prostate cancers.
Learn metastatic and primary tumor tissue processing and clinical annotation in patients with locally advanced and metastatic disease.
Learn to integrate clinical and molecular data as it relates to aggressive variant prostate cancers.
Learn key professional/career skills to complement the research training to develop a comprehensive career path.
ELIGIBILITY REQUIREMENTS
MD or PHD
ADDITIONAL APPLICATION INFORMATION
-Recent MD and/or Ph.D. in cancer biology, cell & molecular biology, or other related fields.
-Prefer candidate with inclination towards translational research.
-At least one first author publication in a peer-reviewed journal stemming from MD and/or PhD studies is required.
-Prefer candidate with knowledge in data science techniques (bioinformatic analyses of genomic-, epigenomic- and proteomic data).
-Prefer candidate with skills in clinical data and patient sample database curation and management.
Interested applicants can obtain additional information at the event held on 5/16. Info at www.postdochouston.org
Please refer to pubs (Aparicio - PMIDs: 38488813, 31515154, 26546618, 23649003, 38136389; Soundararajan - PMIDs: 35805010, 29600194, 38589919, 37686633).
POSITION INFORMATION
MD Anderson follows the NIH stipend levels as outlined by the Kirchstein - NRSA (https://grants.nih.gov/grants/guide/notice-files/NOT-OD-23-076.html) . This full-time trainee position will provide a salary between $56,484 to $68,604, dependent upon the years of postgraduate experience.
MD Anderson offers compensated trainees:
Paid medical benefits (zero premium) starting on first day for trainees who work 30 or more hours per week
Group Dental, Vision, Life, AD&D and Disability coverage
Paid Education Vacation and Sick Leave
Paid institutional holidays, wellness leave, childcare leave and other paid leave programs
Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans
Employer paid life, AD&D and an illness-related reduced salary pay program
Health Savings Account and Dependent Care Reimbursement flexible spending accounts
Fertility benefits
State of Texas longevity pay
Extensive wellness, fitness, employee health programs and employee resource groups
FACULTY MENTOR
Dr. Aparicio (GU) and basic/translational faculty Dr. Soundararajan (TMP)