MD Anderson Cancer Center Postdoctoral Fellow (The Cata Lab) in MDA-On-Site, United States
Dr. Cata lab is looking in candidates interested in learning, coordinating and conducting clinical research in the Department of Anesthesiology & Perioperative Medicine. Dr. Cata lab has more than a dozen of clinical trials in which successful candidate will have the opportunity to collaborate with members of his team and anesthesiologists of the department.
The trainee will learn:
Study Objectives: Clearly define the primary and secondary objectives of the trial. The primary objective is usually the main outcome the trial aims to measure (e.g., effectiveness, safety), while secondary objectives may include additional endpoints.
Study Population: Specify the criteria for participant inclusion and exclusion. This ensures that the study population is representative of the target patient group and that results can be generalized to that population.
Randomization: Random assignment of participants to different treatment groups helps minimize bias and ensures that the groups are comparable at baseline. This is essential for drawing valid conclusions about the treatment's effects.
Control Group: Establish a control group (placebo or standard treatment) against which the experimental treatment is compared. This allows researchers to assess the relative efficacy and safety of the new intervention.
Blinding: Implement blinding (single-blind or double-blind) to reduce bias. In a single-blind trial, participants are unaware of their treatment assignment, while in a double-blind trial, both participants and researchers are unaware.
Endpoint Selection: Clearly define the primary and secondary endpoints, which are the specific outcomes or events that the trial aims to measure. Endpoints should be relevant, reliable, and clinically meaningful.
Sample Size Calculation: Determine the appropriate sample size to achieve statistical power. A larger sample size increases the ability to detect real differences and enhances the generalizability of study findings.
Randomization and Allocation Concealment: Describe the randomization process and how allocation concealment is maintained to prevent selection bias.
Study Phases: Clinical trials typically progress through phases, including Phase I (safety), Phase II (efficacy and dosing), Phase III (large-scale efficacy), and Phase IV (post-marketing surveillance). Each phase serves a specific purpose in the drug development process.
Ethical Considerations: Comply with ethical standards and obtain informed consent from study participants. Ethical review boards oversee the design and conduct of clinical trials to ensure the protection of participants' rights and well-being.
Data Collection and Analysis: Define the methods for data collection and analysis. Statistical methods should be pre-specified to avoid data-driven results.
Adverse Event Monitoring: Establish procedures for monitoring and reporting adverse events. Safety is a critical aspect of clinical trials, and protocols should detail how adverse events will be recorded and managed.
The candidate should hold a Medical Degree (MD) or PhD obtained in the United States or in foreign institution. Candidates should demonstrate a strong interest in clinical research and a clear understanding of the specific research area of the fellowship program. This may involve submitting a research proposal or explaining how their background aligns with the goals of the fellowship.
MD Anderson follows the NIH stipend levels as outlined by the Kirchstein - NRSA (https://grants.nih.gov/grants/guide/notice-files/NOT-OD-23-076.html) . This full-time trainee position will provide a salary between $56,484 to $68,604, dependent upon the years of postgraduate experience.
MD Anderson offers compensated trainees:
Paid medical benefits (zero premium) starting on first day for trainees who work 30 or more hours per week
Group Dental, Vision, Life, AD&D and Disability coverage
Paid Education Vacation and Sick Leave
Paid institutional holidays, wellness leave, childcare leave and other paid leave programs
Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans
Employer paid life, AD&D and an illness-related reduced salary pay program
Health Savings Account and Dependent Care Reimbursement flexible spending accounts
State of Texas longevity pay
Extensive wellness, fitness, employee health programs and employee resource groups